Chinangwa Kuongorora mhedzisiro uye chikamu chechikamu cheAgkistrodon acutus venom ACTX-8 pane adhesion uye kupinda kwecervical cancer cell Hela.
Shutdown system.Nzira dzeFibronectin dzakaputirwa mu96-tsime ndiro.Masero eHela akapfuura nepakati pe0, 2.5, 5, 10, 20, 40 g/ml yeACTX-8.
Mushure mekurapa, kusungirirwa neFibronectin kwakaonekwa, uye nhamba yemasero anonamatira akaonekwa neMTY;Kuonekwa kwekupinda kwesero uye kutama neTransweU cell nzira
Shanduko mumano;Iyo yemakwikwi inosunga pakati peACTX-8 neFibronectin uye Hela cell membrane yakaonekwa nekuyerera cytometry.Mhinduro:
Mushure mekurapwa neACTX-8, kunamatira kweHela masero kuFibronectin kwakadzikira, uye transwell cell kuyedza yakaratidza kuti Hela masero akatama.
Kugona kwekufamba uye kupinda kunoderedzwawo.Iyo inoyerera cytometry mhedzisiro inoratidza kuti ACTX-8 inogona kukwikwidza kusunga iyo receptor yeFibronectin pachitokisi.
Nguva yekutumira: Feb-18-2023