Kuparadzaniswa kweanticoagulant uye fibrinolytic zvikamu kubva kuAgkistrodon halys venom uye nemhedzisiro yavo paropa coagulation system.

Kudzidza mhedzisiro ye thrombin senge enzyme uye plasmin yakaparadzaniswa nehuturu hweAgkistrodon acutus paropa coagulation system Nzira: Thrombin senge enzyme uye plasmin yakaparadzaniswa uye yakacheneswa kubva kuAgkistrodon acutus venom neDEAE Sepharose CL-6B uye Sephadex G-75 chromatography, uye mhedzisiro yavo pa coagulation system yakaonekwa kuburikidza ne in vivo kuyedza Mhedzisiro: Thrombin senge enzyme uye plasmin yakaparadzaniswa kubva kune uturu hweAgkistrodon acutus, uye huremu hwavo hwemamorekuru hwaive 39300 uye 26600 zvichiteerana.In vivo ongororo dzakaratidza kuti thrombin senge enzyme uye plasmin kubva kuAgkistrodon acutus venom inogona kurebesa nguva yese yekugwamba kweropa, activated partial prothrombin nguva, thrombin nguva uye prothrombin nguva, uye kuderedza zviri mufibrinogen, asi mhedzisiro yethrombin senge enzyme yaive yakasimba. , Zvisinei, fibrinolytic enzyme yakaratidza anticoagulant effect chete pachiyero chikuru, uye kusanganiswa kwezviviri kwaiva nani pane kushandiswa kwavo kumwe chete.Mhedziso: Thrombin senge enzyme uye fibrinolytic enzyme kubva kuAgkistrodon acutus venom ine