Uturu hwenyoka hune zvakawanda bioactive components, kunyanya kusanganisira protease uye polypeptide
Inoita 90% ~ 95% yehuremu hwakaoma hwehuturu hwenyoka [l
Nekuenderera mberi kwekuvandudza tekinoroji, mapuroteni mazhinji ebiological anoshanda muhuturu hwenyoka zvishoma nezvishoma
Yakaparadzaniswa uye yakacheneswa, uye vanhu vakaita
Ita tsvakiridzo yakadzama pazviri nechinangwa chekushandisa mishonga inoshanda muhuturu hwenyoka kuvanhu.
Mukurapa kwezvirwere zvakafanana.Parizvino, mishonga inoshanda yemishonga inoshanda iri muhuturu hwenyoka
Tsvagiridzo yezvinodhaka uye kiriniki application inoitwa inonyanya kutarisana neantithrombotic, hemostatic uye hypoglycemic
Pressure, anti-cancer uye painkillers.
L Antithrombotic zvinodhaka
Huru hwenyoka protease ine anti-thrombotic uye thrombolytic mhedzisiro inonyanya kusanganisira Ancelor.
Enzyme (hoe crod), batmxobin, defibrase (de coerase) uye Agkistrodon acutus
Enzyme (autobin).Zvitatu zvekutanga ndezve snaI [e venom
Thmmbin senge enzynles, s Ⅷ.E), sVTLE is serine protease, zvakafanana ne
Ine arginine esterase uye amidase chiitiko - 1. Snake venom thrombin-like enzyme
Inoshanda pafibrinogen kuburitsa fibrinogen A kana B, nekudaro
Inogona coagulate iyo polymerization yefibrin monomer musoro nemuswe, nekuti inoratidza thrombin.
Inoshanda uye inonzi thrombin-like.Panguva imwecheteyo, huturu hwenyoka thrombin-senge enzyme haigone kuwanikwa muvanhu
Inomisikidza coagulation factor x Ⅲ in vivo, uye iyo fibrin monomer inogadzirwa nehydrolysis yayo inogona.
Musoro uye muswe polymerization, asi haigone kuburitsa parutivi cheni muchinjiko-inongedzo, iri nyore kukuvadzwa neakasikwa reticuloendothelial system.
Iyo plasma fibrinogen level yakaderedzwa nekuda kwe phagocytosis kana kuderedzwa ne fibrinolytic system
Iyo iri mu benign fibrinolytic state, saka inoratidza anticoagulation uye kuora mwoyo mumuviri
Fibrillation H1.Agkistrodon acutus enzyme ndeye fibrinolytic enzyme, iyo inonzi fibrinolytic
Chidimburiko cheiyo enzyme [Erin (ogen) ol "icenzyme, FLE] inogona kupatsanurwa kuita imwe-cheni
Zinc metalloproteinase uye single-chain kana kaviri-chain serine protease, kunyanya zinc simbi zai.
White enzyme.Nyoka uturu fibrinolytic enzyme haidi activation ye activator, uye inogona kucheka zvakananga fibers.
Protein (protogen) inogadzira hemofibrin, saka haizokonzerese kuungana “J.
Kubva muhuturu hweAgkistrodon halys (semuenzaniso sek, № r [md ∞ kuenda, ngarava) muMalaysia
Iyo yakasarudzika ankylose ndiyo yekutanga kushandiswa mukurapa kwechirwere chethrombotic
SVTLE mushonga.6 J. Mushure mekuvandudzwa kweAncelose, yakambodzidzwa nenyika dzakawanda
Vatsvakurudzi vanotenda kuti sV'11E ndiyo inonyanya kuvimbisa mushonga wekurapa zvirwere zvethrombotic,
Pamusoro pekushandiswa pakurapa kweperipheral thrombosis, inogona zvakare kushandiswa pakurapa yakadzika venous thrombosis uye yepakati venous thrombosis.
Pulse thrombosis inewo mushonga wekurapa "J.Pakazosvika ma1990, nyika dzakawanda nematunhu
Qu Du inofarira zvikuru kurapwa kweacute cerebral ischemia uye sitiroko ine aclase, uye
Fund project: Military Medical Science and Technology Youth Cltivation Project (13QNP068);Hondo yose “12
5 “general medical research project (cwslJ280);Chengdu Military Dunhu "12th Five-Yemakore Chirongwa" Medical Research
Zvirongwa zvakakosha (B12026);Zvakawanda zvekutsvagisa zvekurapa chirongwa cheChengdu Military Dunhu panguva yegumi nemaviri Chirongwa cheMakore mashanu
(C12062)
Chikwata chemunyori: 650032 Kunming, Chengdu Military Region Center yeChirwere Chekudzivirira uye Kudzivirira (Zhang Zhixiao,
Hu Tingsong, Cui Qinghua, Zheng Ying, Fan Quanshui);Pathogens, Chikoro cheMushonga Wekutanga, Youjiang Medical College yeNyika
Biology uye Immunology Dzidziso uye Hofisi Yekutsvagisa (Xie Zhenfeng)
Anoenderana munyori: Fan Quanshui, E-mail: fqsl68@126 ．com
Zviverengero zvidiki-zvidiki zvekiriniki application zvidzidzo zvakaitwa.Kutanga kushandiswa kwezvinodhaka evaluation index
Uye zvakare, Ancelose inogona kushandiswa mukurapa kwekiriniki yevarwere vane acute ischemic sitiroko padanho rekutanga
Inoratidza zvakanaka kurapa maitiro.Mushure mezvo, nehombe-yakakura randomized kaviri-mapofu, placebo peya
Maererano nekiriniki yekuedza, iye, nezvimwewo. Kune 2613 zviitiko zveacute
Mishonga yekurapa mhedzisiro yevarwere vane bonde ischemic sitiroko yakasimbisa kuti varwere vari muboka recloroxobin
Chiyero chekupona chakawedzera zvakanyanya, asi njodzi yekubuda ropa mucranial yakawedzerawo.Mushure maizvozvo
Muedzo wekiriniki wevarwere ve1222 vane acute ischemic sitiroko yakasimbisa kuti mushure memaawa matatu
Ancelose haina kukurudzirwa kurapwa.1…. United States neCanada yakaburitswa muna 2009
500 shamhu dzinosanganisira nyika gumi nembiri uye matunhu anosanganisira Canada neAustralia
kutambura kubva
Nguva yekutumira: Feb-26-2023