Kuparadzaniswa kweanticoagulant uye fibrinolytic zvikamu kubva kuAgkistrodon acutus venom uye mhedzisiro yayo paropa coagulation system.

[Abstract] Chinangwa: Kudzidza maitiro e-thrombin-like uye fibrinolytic enzymes akaparadzaniswa uye akacheneswa kubva kune imwechete Agkistrodon acutus venom paropa coagulation system.Nzira: The thrombin-like uye fibrinolytic enzymes akaparadzaniswa uye akacheneswa kubva kuAgkistrodon acutus venom neDEAE-Sepharose CL-6B uye Sephadex G-75 chromatography, uye mhedzisiro yezvose zviri paropa coagulation system indexes yakaonekwa kuburikidza mu vivo kuedza.Migumisiro: Chimwe chikamu chethrombin-like uye fibrinolytic enzymes zvakaparadzaniswa uye zvakacheneswa kubva kuAgkistrodon acutus venom, Huremu hwavo hwema molecular 39300 uye 26600, zvichiteerana.In vivo kuedza kwakaratidza kuti zvose thrombin-like uye fibrinolytic enzymes kubva kuAgkistrodon acutus venom inogona kurebesa nguva yose yeropa coagulation, activated partial prothrombin time, thrombin nguva uye prothrombin nguva, uye kuderedza zviri mufibrinogen, asi basa rethrombin- semaenzayimu akasimba, nepo fibrinolytic enzymes inongoratidza anticoagulant mhedzisiro pamadosi makuru, Mhedziso: Enzyme yeThrombin-senge enzyme uye fibrinolytic enzyme kubva kuAgkistrodon acutus venom ine mhedzisiro paiyo ropa coagulation system mumhuka, uye kusanganiswa kwezviviri kune pachena anticoagulant mhedzisiro.