Uturu hwenyoka imvura inovanzwa nenyoka dzine uturu kubva mumatumbu adzo.Chikamu chayo chikuru ipuroteni ine chepfu, inoverengera 90% kusvika 95% yehuremu hwakaoma.Kune marudzi makumi maviri emaenzayimu uye chepfu.Pamusoro pezvo, inewo mamwe madiki mamorekuru peptides, amino acids, makabhohaidhiretsi, lipids, nucleosides, biological amines uye simbi ions.Kuumbwa kwehuturu hwenyoka kwakaoma kwazvo, uye huturu, pharmacology uye toxicological mhedzisiro yehuturu hwenyoka hwakasiyana vane maitiro avo.Pakati pavo, chepfu inoratidzwa sezvinotevera: 1. Ropa rinotenderera chepfu: (kusanganisira viper venom, agkistrodon acutus venom, caltrodon venom, green snake venom) 2. Neurotoxins: (uturu hwenyoka yeziso, mhete yegoridhe yenyoka uturu, silver ring nyoka uturu , huturu hwenyoka, huturu hwenyoka) 3 Musanganiswa wehuturu: (Agkistrodon halys venom, Ophiodon halys venom) ① Anti-gomarara mhedzisiro yehuturu hwenyoka: gomarara chimwe chezvirwere zvitatu zvikuru zvinoisa hutano hwevanhu, uye hapana mushonga unoshanda. present.Vesainzi kubva kunyika dzese vari kutora ongororo yehuturu hwenyoka senzira itsva yekukunda chipingamupinyi ichi.Iyo Snake Venom Research Office yeChina Medical University iri kuyedza kutsvaga zvinoshanda zvinogona kutadzisa bundu kukura kubva kuAgkistrodon halys venom inogadzirwa muDalian, Liaoning, Muedzo wekufananidza tumor inhibition wakaitwa pakati pehuturu hwepakutanga nehuturu hwakasarudzika hweAgkistrodon halys Pallas. .Zvipfumbamwe zvakasiyana-siyana zvehuturu hwenyoka zvine madhigirii akasiyana ekudzivisa pambeva sarcomas, uye chiyero chekudzivirira bundu chakakwira se87.1%.② Anticoagulant mhedzisiro yehuturu hwenyoka: iyo "defibrase" yakatorwa kubva muhuturu hweAgkistrodon halys acutus muYunnan, China, yakapfuura chiziviso chehunyanzvi muna 1981, uye yakashandiswa kurapa mazana matatu nemakumi matatu nemakumi matatu ezviitiko zvevascular thrombosis, kusanganisira 242 kesi dzecerebral thrombosis. chiyero chinoshanda i86.4%.Iyo Agkistrodon halys antacid yakagadzirwa neChina Medical University neShenyang Pharmaceutical College mukushandira pamwe yakawana zvinogutsa mhedzisiro yekiriniki mukurapa kwevascular occlusive zvirwere.Iyo antacid yehuturu hwenyoka yakagadzirwa neSnake Venom Research Office yeChina Medical University inogona kuderedza lipids yeropa, kuwedzera tsinga dzeropa, kuderedza zviri mu thromboxane muropa, kuwedzera prostacyclin, uye kuzorodza vascular smooth muscle.Iyo yakanaka anti-.③ Kana iri yehemostatic mhedzisiro yehuturu hwenyoka, Japan inoshandisa coagulant inokurudzira musanganiswa inotaurwa munyoka kuti ishandiswe pakuvhiyiwa kwekiriniki, mushonga wemukati, chimiro chechiso, gynecology uye obstetrics nezvimwe zvirwere zvehemorrhagic.Mushonga unonzi "reptilin injection".④ Kugadzirira kweantivenin serum: Kugadzirwa kweantivenin serum muChina kwakatanga muma1930s.Mushure mekusunungurwa, Shanghai Institute of Biological Products, yakabatana neSnake Research Group yeZhejiang Medical University, Zhejiang Institute of Traditional Chinese Medicine, uye Guangzhou Medical College, yakabudirira kugadzirira yakanatswa antivenin serum yeAgkistrodon halys, Agkistrodon acutus, Bungarus multicinctus, uye Ophthalmus.⑤ Analgesic effect yehuturu hwenyoka: Muna 1976, Yunnan Kunming Animal Research Institute yakabudirira kugadzira "Ketongling" kubva muhuturu hwenyoka, iyo inoshandiswa kurapa zvirwere zvakasiyana-siyana zvinorwadza uye yakawana yakasarudzika analgesic effect.Iyo "compound Ketongning" yakagadzirwa naCao Yisheng yakaratidza kushanda kwakanaka mukurapa marwadzo etsinga, kurwadziwa kwekenza uye detoxification.Nekuda kwekuti huturu hwenyoka hune analgesic hwakanyanya uye hahupindwe muropa, hunoshandiswa nekiriniki kutsiva morphine mukurapa marwadzo egomarara.Uturu hwehuturu hunogona kushandiswa kugadzira yakakosha anti-venom serum, analgesics uye hemostatic agents.Mhedzisiro yaro iri nani pane morphine uye dolantin, uye haina kupindwa muropa.Uturu hwenyoka hunogonawo kurapa mitezo uye polio.Mumakore achangopfuura, huturu hwenyoka hwave huchishandiswa kurapa gomarara.Nekuti uturu hwenyoka musanganiswa unoumbwa nemapuroteni makumi matatu nemana, imwe yacho yakakosha uye nhamba huru yehupfu inonzi cytolysin.Iyo muchetura unonyanya kuparadza maseru uye maseru membranes.Izvi zvinogadzira mamota akaipa.Kana iyo cytolysin kubva kuhuturu hwenyoka ikaparadzaniswa uye yakaiswa mumuviri wemunhu kuti ipararire muviri wese nekutenderera kweropa kuti iuraye masero egomarara, pane tariro huru yekukunda kuoma kwekurapwa kwegomarara.Iyo defibrase yejekiseni inotorwa kubva muhuturu hweAgkistrodon acutus kuChina.Iine basa rekudzikisa fibrinogen uye thrombolysis, uye mushonga unokosha wekurapa zvirwere zvemwoyo.Mashandisirwo makuru masere ehuturu hwenyoka ndeaya: 1. kurapwa kwegomarara uye anticancer, anti-bundu;2. Hemostasis uye
Nguva yekutumira: Feb-11-2023