[Abstract] Chinangwa Kuongorora inhibitory mhedzisiro yediki molecular polypeptide chikamu (K chikamu) kubva kuAgkistrodon acutus uturu pakupararira kwemunhu ovarian cancer cell line A2780 uye maitiro ayo.Nzira MTT assay yakashandiswa kuona kukura inhibition yeK chikamu pane kenza cell mitsara;Iyo anti-cell adhesion effect yeK chikamu yakaonekwa nekunamatira test;AO-EB yakapetwa kaviri fluorescence staining uye kuyerera cytometry yakashandiswa kuona kuitika kweapoptosis.Mhinduro K chikamu chakadzivisa kuwanda kwekenza yekenza yemunhu yekenza A2780 muhukama hwenguva-yekuita uye dose-effect, uye inogona kuramba kunamatira kwemasero kuFN.Apoptosis yakaonekwa neAO-EB kaviri fluorescence staining uye kuyerera cytometry.Mhedziso Chikamu K chine inhibitory yakakosha pakupararira kwekenza yegomarara remunhu A2780 in vitro, uye maitiro ayo anogona kunge ane chekuita ne-anti-cell adhesion uye induction yeapoptosis.
Nguva yekutumira: Jan-11-2023